Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Protéines
CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes.
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Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) protein (His tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 91-190) protein (GST tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) protein (His tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protéine Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) protein (DYKDDDDK Tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protéine Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (Active) Protéine Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protéine Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 236-472) (Active) protein (His tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protéine Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) protein (His tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) protein (His tag) Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protéine Protein
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protéine Protein
Profil protéine Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
Profil protéine
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene names and symbols associated with CYP2D6
- cytochrome P450 family 2 subfamily D member 6 (CYP2D6) anticorps
- cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) anticorps
- cytochrome 2D6 (CYP2D6) anticorps
- cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) anticorps
- cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S) anticorps
- cytochrome P450 family 2 subfamily D member 6 (cyp2d6) anticorps
- cytochrome P450 2D6 (CYP2D6) anticorps
- cytochrome P450 2D6-like (LOC100988273) anticorps
- CPD6 anticorps
- CYP2D anticorps
- cyp2d2 anticorps
- CYP2D6 anticorps
- cyp2d6-a anticorps
- CYP2D7AP anticorps
- CYP2D7BP anticorps
- CYP2D7P2 anticorps
- CYP2D8P2 anticorps
- CYP2D42 anticorps
- CYP2DL1 anticorps
- CYPIID6 anticorps
- MGC64445 anticorps
- P450-DB1 anticorps
- P450C2D anticorps
- P450DB1 anticorps
Protein level used designations for CYP2D6
cytochrome P450 2D6 , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , debrisoquine 4-hydroxylase , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , cytochrome P450 2D6-like
GENE ID | SPECIES |
---|---|
1565 | Homo sapiens |
470228 | Pan troglodytes |
678691 | Macaca mulatta |
100500743 | Felis catus |
379479 | Xenopus laevis |
446878 | Xenopus laevis |
548436 | Xenopus (Silurana) tropicalis |
100568286 | Ovis aries |
100988273 | Pan paniscus |
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