Rat (Rattus) CYP2E1 Kit ELISA pour Sandwich ELISA - ABIN416199
:
Salama, Abdulla, Alrashdi, Hadi: Mechanism of Hepatoprotective Effect of Boesenbergia rotunda in Thioacetamide-Induced Liver Damage in Rats. dans Evidence-based complementary and alternative medicine : eCAM 2013
(PubMed)
Show all 7 references for ABIN416199
Mouse (Murine) CYP2E1 Kit ELISA pour Sandwich ELISA - ABIN857678
:
Possamai, McPhail, Khamri, Wu, Concas, Harrison, Williams, Cox, Cox, Anstee, Thursz: The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity. dans Liver international : official journal of the International Association for the Study of the Liver 2014
(PubMed)
Show all 2 references for ABIN857678
The localization of CYP1A2 (Montrer CYP1A2 Kits ELISA), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98
The CYP2E1-PPARalpha (Montrer PPARA Kits ELISA) axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function
Results demonstrated that CYP2E1*5B and CYP2E1*6 minor alleles play a role in the development of sporadic colorectal neoplasms.
This meta-analysis suggests that there is an increased risk of antituberculosis drug-induced hepatotoxicity in individuals carrying the C1/C1 genotype of the CYP2E1 RsaI/PstI (Montrer SPINK1 Kits ELISA) polymorphism; however, no association was found for the DraI polymorphism
NS5A contributes to reactive oxygen species production by activating expression of NADPH (Montrer NQO1 Kits ELISA) oxidases 1 and 4 as well as cytochrome P450 2E1.
This meta-analysis suggests that the CYP2E1 polymorphisms contributed to the susceptibility of nasopharyngeal carcinoma, especially in Asian populations.
Study indicate that ALDH2 (Montrer ALDH2 Kits ELISA) Glu487Lys and CYP4502E1 polymorphisms could be risk factors for the development of gastric cancer in the Chinese population.
genetic association studies in population in Italy: Data suggest that SNPs in CYP2E1 are associated with differentiated thyroid carcinoma.
CYP2E1 RsaI/PstI (Montrer SPINK1 Kits ELISA) polymorphisms may modify the susceptibility to HNC (Montrer MMP8 Kits ELISA), particularly among Asians, mixed population, and never-smokers.
CYP2E1 rs2031920 and COMT (Montrer COMT Kits ELISA) rs4680 are not major contributors to lung cancer risk.
Single nucleotide polymorphism in CYP2E1 gene is Associated with Breast Cancer.
Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.
Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (Montrer DHCR24 Kits ELISA)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (Montrer DHCR24 Kits ELISA)-induced liver damage
CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.
Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice
Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (Montrer TP53 Kits ELISA), p21, CCND1 (Montrer CCND1 Kits ELISA), PCNA (Montrer PCNA Kits ELISA), and BCL-2 (Montrer BCL2 Kits ELISA) to promote liver regeneration.
Studied hepatic stellate cell cytoglobin (Montrer CYGB Kits ELISA) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.
Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.
The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.
significant increases in Col1a1 (Montrer COL1A1 Kits ELISA), serine/threonine-protein kinase 1, Ctnnb1 (Montrer CTNNB1 Kits ELISA), CSRNP1, Ddit4 (Montrer DDIT4 Kits ELISA), Cyp2e1, and Krit1 (Montrer KRIT1 Kits ELISA) expressions and great decreases inreceptor D2, Neu1, and Dhcr7 (Montrer DHCR7 Kits ELISA) expressions following long-term exposure to TiO2 NPs (Montrer NPS Kits ELISA)
ATF4 (Montrer ATF4 Kits ELISA) expression in the liver is responsible for the protective effects against high fat diet-induced CYP2E1 expression.
A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.
The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1
| GENE ID | SPECIES |
|---|---|
| 100066422 | Equus caballus |
| 554344 | Felis catus |
| 6345684 | Pyrenophora tritici-repentis Pt-1C-BFP |
| 100342572 | Oryctolagus cuniculus |
| 100727914 | Cavia porcellus |
| 101843716 | Mesocricetus auratus |
| 1571 | Homo sapiens |
| 415128 | Canis lupus familiaris |
| 13106 | Mus musculus |
| 25086 | Rattus norvegicus |
| 403216 | Sus scrofa |
| 282213 | Bos taurus |
| 100568285 | Ovis aries |
| 678688 | Macaca mulatta |