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ACSL4 Produits

(Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Catégories

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].

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Catégories ACSL4 en vedette

ACSL4 Anticorps

High quality antibodies with extensive validation data.

ACSL4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ACSL4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (7)
N° du produit ABIN6136458
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC, IP
Validations
  • (3)
  • (8)
N° du produit ABIN2854678
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (7)
N° du produit ABIN7265424
Quantité 100 μL
Fiche technique Fiche technique

ACSL4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN419350
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6212507
Quantité 96 tests
Fiche technique Fiche technique

ACSL4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1305715
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305717
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3088626
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ACSL4

Ndiaye, Liu, Hall, Minogue, Morgan, Waugh: "Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases." dans: Bioscience reports, Vol. 40, Issue 4, (2020) (PubMed).

Garcia-Bermudez, Baudrier, Bayraktar, Shen, La, Guarecuco, Yucel, Fiore, Tavora, Freinkman, Chan, Lewis, Min, Inghirami, Sabatini, Birsoy: "Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death." dans: Nature, Vol. 567, Issue 7746, pp. 118-122, (2019) (PubMed).

Zhang, Wang, Cui, Deng, Xu, Yu, Cichello, Serrero, Ying, Liu: "Morphologically and Functionally Distinct Lipid Droplet Subpopulations." dans: Scientific reports, Vol. 6, pp. 29539, (2018) (PubMed).

Nuzzo, Amato, Picone, Terzo, Galizzi, Bonina, Mulè, Di Carlo: "A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice." dans: Nutrients, Vol. 10, Issue 9, (2018) (PubMed).

Radif, Ndiaye, Kalantzi, Jacobs, Hall, Minogue, Waugh: "The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells." dans: Molecular and cellular biochemistry, Vol. 448, Issue 1-2, pp. 275-286, (2018) (PubMed).

Shinjo, Jiang, Nameta, Suzuki, Kanai, Nomura, Goda: "Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance." dans: Experimental cell research, Vol. 359, Issue 1, pp. 86-93, (2017) (PubMed).

Pera, Larrea, Guardia-Laguarta, Montesinos, Velasco, Agrawal, Xu, Chan, Di Paolo, Mehler, Perumal, Macaluso, Freyberg, Acin-Perez, Enriquez, Schon, Area-Gomez: "Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease." dans: The EMBO journal, Vol. 36, Issue 22, pp. 3356-3371, (2017) (PubMed).

Yuan, Li, Zhang, Kang, Tang: "Identification of ACSL4 as a biomarker and contributor of ferroptosis." dans: Biochemical and biophysical research communications, Vol. 478, Issue 3, pp. 1338-43, (2016) (PubMed).

Marzesco, Flötenmeyer, Bühler, Obermüller, Staufenbiel, Jucker, Baumann: "Highly potent intracellular membrane-associated Aβ seeds." dans: Scientific reports, Vol. 6, pp. 28125, (2016) (PubMed).

Williamson, Wong, Bozidis, Zhang, Colberg-Poley et al.: "Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected ..." dans: Current protocols in cell biology, Vol. 68, pp. 3.27.1-33, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à ACSL4

acyl-CoA synthetase long chain family member 4a (acsl4a), acyl-CoA synthetase long-chain family member 4 (ACSL4), acyl-CoA synthetase long chain family member 4 (ACSL4), AcsL4 (acsL4), acyl-CoA synthetase long chain family member 3 (acsl3), Long-chain-fatty-acid--CoA ligase 4 (acsl4), acyl-CoA synthetase long-chain family member 4 (Acsl4), acyl-CoA synthetase long-chain family member 4 S homeolog (acsl4.S), AMP-dependent synthetase and ligase family protein (LACS4), 9430020A05Rik, ACS4, Acs4, acs4, acsl3, acsl4, ACSL4, AU018108, FACL4, Facl4, facl4, LACS4, Lacs4, lacs4, long-chain acyl-CoA synthetase 4, MRX63, mrx63, MRX68, mrx68, T32A16.20, T32A16_20, zgc:66186

Protein level used designations for ACSL4

  • acyl-CoA synthetase long-chain family member 4
  • long-chain-fatty-acid--CoA ligase 4
  • AcsL4
  • Long-chain-fatty-acid--CoA ligase 4
  • long-chain-fatty-acid--CoA ligase 4-like
  • LACS 4
  • acyl-CoA synthetase 4
  • fatty-acid-Coenzyme A ligase, long-chain 4
  • lignoceroyl-CoA synthase
  • long-chain acyl-CoA synthetase 4
  • long-chain fatty-acid-Coenzyme A ligase 4
  • fatty acid-Coenzyme A ligase, long chain 4
  • mACS4
  • fatty acid Coenzyme A ligase, long chain 4
  • fatty acid-Coenzyme A ligase long chain 4
  • acyl-CoA synthetase long-chain family member 3
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