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ACSL5 Produits

(Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5))

Catégories

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories ACSL5 en vedette

ACSL5 Anticorps

High quality antibodies with extensive validation data.

ACSL5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ACSL5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP, IHC (p)
Validations
  • (4)
  • (6)
N° du produit ABIN565656
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7158511
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
N° du produit ABIN1678546
Quantité 100 μg
Fiche technique Fiche technique

ACSL5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6212508
Quantité 96 tests
Fiche technique Fiche technique

ACSL5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305719
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305721
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3119063
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ACSL5

Bauer, Duca, Waise, Dranse, Rasmussen, Puri, Rasti, OBrien, Lam: "Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis." dans: Cell metabolism, Vol. 27, Issue 3, pp. 572-587.e6, (2018) (PubMed).

Yu, Zhang, Cui, Wang, Na, Zhu, Li, Xu, Yang, Christian, Liu: "Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment." dans: Biochimica et biophysica acta, Vol. 1853, Issue 5, pp. 918-28, (2015) (PubMed).

Klaus, Kaemmerer, Reinartz, Schneider, Plum, Jeon, Hose, Hartmann, Schnölzer, Wagner, Kopitz, Gassler: "TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas." dans: Cell and tissue research, Vol. 357, Issue 1, pp. 267-78, (2014) (PubMed).

Klaus, Schneider, Hedberg, Schütz, Bernhagen, Waldmann, Gassler, Kaemmerer: "Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity." dans: World journal of gastroenterology : WJG, Vol. 20, Issue 40, pp. 14855-64, (2014) (PubMed).

Klett, Chen, Edin, Li, Ilkayeva, Zeldin, Newgard, Coleman: "Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion." dans: The Journal of biological chemistry, Vol. 288, Issue 30, pp. 21618-29, (2013) (PubMed).

Mashima, Sato, Sugimoto, Tsuruo, Seimiya: "Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions." dans: Oncogene, Vol. 28, Issue 1, pp. 9-19, (2009) (PubMed).

Tripodi, Quéméner, Renaudin, Ferron, Malard, Guisle-Marsollier, Sébille-Rivain, Verger, Géraut, Gratas-Rabbia-Ré: "Gene expression profiling in sinonasal adenocarcinoma." dans: BMC medical genomics, Vol. 2, pp. 65, (2009) (PubMed).

Obermüller, Keith, Kopitz, Autschbach, Schirmacher, Gassler: "Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5." dans: International journal of colorectal disease, Vol. 21, Issue 2, pp. 130-4, (2006) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." dans: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Minekura, Kang, Inagaki, Suzuki, Sato, Fujino, Yamamoto: "Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene." dans: Gene, Vol. 278, Issue 1-2, pp. 185-92, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à ACSL5

acyl-CoA synthetase long chain family member 5 (ACSL5), acyl-CoA synthetase long chain family member 5 (acsl5), acyl-CoA synthetase long chain family member 5 (Acsl5), acyl-CoA synthetase long-chain family member 5 (Acsl5), acyl-CoA synthetase long-chain family member 5 (ACSL5), 1700030F05Rik, acs2, ACS2, acs5, ACS5, Acs5, ACSL5, facl5, FACL5, Facl5, zgc:92083

Protein level used designations for ACSL5

  • acyl-CoA synthetase long-chain family member 5
  • long-chain-fatty-acid--CoA ligase 5
  • acyl-CoA synthetase 5
  • long-chain-fatty-acid--CoA ligase 5-like
  • FACL5 for fatty acid coenzyme A ligase 5
  • LACS 5
  • fatty acid coenzyme A ligase 5
  • fatty-acid-Coenzyme A ligase, long-chain 5
  • long-chain acyl-CoA synthetase 5
  • long-chain fatty acid coenzyme A ligase 5
  • fatty acid Coenzyme A ligase, long chain 5
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