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ADAM17 Produits

(ADAM Metallopeptidase Domain 17 (ADAM17))
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008].

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Catégories ADAM17 en vedette

ADAM17 Anticorps

High quality antibodies with extensive validation data.

ADAM17 Kits ELISA

Reliable ELISA kits for a wide range of species.

ADAM17 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ADAM17 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (8)
N° du produit ABIN7426310
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), PLA
Validations
  • (1)
  • (5)
N° du produit ABIN563080
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (4)
N° du produit ABIN705671
Quantité 100 μL
Fiche technique Fiche technique

ADAM17 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (5)
N° du produit ABIN6730919
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6974750
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953448
Quantité 96 tests
Fiche technique Fiche technique

ADAM17 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121690
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305853
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3088567
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ADAM17

Six, Debaene, Van den Hauwe, De Rycke, Gardiner, Compernolle, Feys: "GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate." dans: Journal of thrombosis and haemostasis : JTH, (2023) (PubMed).

Beke Debreceni, Szász, Kónya, Erdődi, Kiss, Kappelmayer: "L-Selectin Expression is Influenced by Phosphatase Activity in Chronic Lymphocytic Leukemia." dans: Cytometry. Part B, Clinical cytometry, Vol. 96, Issue 2, pp. 149-157, (2020) (PubMed).

Yousef, Saleh, Abd-Allah, Elnagar, Akool: "PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice." dans: Chemico-biological interactions, Vol. 330, pp. 109245, (2020) (PubMed).

Dreschers, Platen, Ludwig, Gille, Köstlin, Orlikowsky: "Metalloproteinases TACE and MMP-9 Differentially Regulate Death Factors on Adult and Neonatal Monocytes After Infection with Escherichia coli." dans: International journal of molecular sciences, Vol. 20, Issue 6, (2019) (PubMed).

Hirayama, Awano, Seta, Ansai: "ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes." dans: Biomedical research (Tokyo, Japan), Vol. 38, Issue 3, pp. 157-165, (2018) (PubMed).

Lécuyer, Virion, Barnier, Matczak, Bourdoulous, Bianchini, Saller, Borgel, Nassif, Coureuil: "An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans." dans: PLoS pathogens, Vol. 14, Issue 4, pp. e1006981, (2018) (PubMed).

Wang, Wang, Yin, Zhang, Yu, Kong, Yuan, Fang, Liu, Liu, Shi: "Reduced neurotrophic factor level is the early event before the functional neuronal deficiency in high-fat diet induced obese mice." dans: Metabolic brain disease, Vol. 32, Issue 1, pp. 247-257, (2018) (PubMed).

Sun, Jiang, Lu, Chen, Tao, Chen: "Therapeutic potential of ADAM17 modulation in gastric cancer through regulation of the EGFR and TNF-α signalling pathways." dans: Molecular and cellular biochemistry, Vol. 426, Issue 1-2, pp. 17-26, (2017) (PubMed).

Serra, Gallelli, Butrico, Buffone, Caliò, De Caridi, Massara, Barbetta, Amato, Labonia, Mimmi, Iaccino, de Franciscis: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." dans: International wound journal, (2016) (PubMed).

Sharma, Bender, Zimmermann, Riesterer, Broggini-Tenzer, Pruschy: "Secretome Signature Identifies ADAM17 as Novel Target for Radiosensitization of Non-Small Cell Lung Cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 17, pp. 4428-39, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à ADAM17

ADAM metallopeptidase domain 17 (ADAM17), a disintegrin and metallopeptidase domain 17 (Adam17), ADAM metallopeptidase domain 17b (adam17b), ADAM metallopeptidase domain 17 L homeolog (adam17.L), ADAM metallopeptidase domain 17 (Adam17), ADAM metallopeptidase domain 17a (adam17a), adam17, ADAM18, adam18, CD156B, CD156b, cd156b, CSVP, csvp, fc20b01, NISBD, si:dkey-81b15.2, TACE, Tace, tace, wu:fc20b01, zgc:63886

Protein level used designations for ADAM17

  • ADAM metallopeptidase domain 18
  • TNF-alpha convertase
  • TNF-alpha converting enzyme
  • disintegrin and metalloproteinase domain-containing protein 17
  • snake venom-like protease
  • tumor necrosis factor, alpha, converting enzyme
  • ADAM 17
  • TNF-alpha-converting enzyme
  • a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme
  • a disintegrin and metalloproteinase domain 17
  • a disintegrin and metallopeptidase domain 17
  • ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)
  • a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)
  • tumor necrosis factor alpha converting enzyme
  • ADAM metallopeptidase domain 17
  • a disintegrin and metalloprotease domain 17
  • disintegrin metalloproteinase
  • disintegrin and metalloproteinase domain-containing protein 17-like
  • ADAM metallopeptidase domain 17a
  • DKEY-174C12.1
  • a disintegrin and metalloproteinase domain 17a
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