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AGE Produits

(Advanced Glycation End Products (AGE))
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008].

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Catégories AGE en vedette

AGE Anticorps

High quality antibodies with extensive validation data.

AGE Kits ELISA

Reliable ELISA kits for a wide range of species.

AGE Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AGE recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, FACS, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (3)
  • (2)
N° du produit ABIN738516
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Human
Application
Validations
N° du produit ABIN3027441
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Various Species
Application WB, IHC, IP, ICC
Validations
N° du produit ABIN7427828
Quantité 100 μL
Fiche technique Fiche technique

AGE recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (23)
  • (1)
N° du produit ABIN6953551
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
N° du produit ABIN6973597
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
N° du produit ABIN6964672
Quantité 96 tests
Fiche technique Fiche technique

AGE recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity General
Source
Validations
N° du produit ABIN1877203
Quantité 50 μg
Fiche technique Fiche technique
Reactivity All Species
Source Human
Validations
N° du produit ABIN6239805
Quantité 50 μg
Fiche technique Fiche technique
Reactivity General
Source Human
Validations
N° du produit ABIN6119733
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AGE

Solé, Marazuela, Castellote, Bonaterra-Pastra, Giménez-Llort, Hernández-Guillamon: "Therapeutic effect of human ApoA-I-Milano variant in aged transgenic mouse model of Alzheimer's disease." dans: British journal of pharmacology, Vol. 180, Issue 15, pp. 1999-2017, (2023) (PubMed).

Liu, Shen, Chen, Cao, Di, Lan, Chen, Bai, Han, Xu: "Inhibition of RAGE by FPS-ZM1 alleviates renal injury in spontaneously hypertensive rats." dans: European journal of pharmacology, pp. 173228, (2020) (PubMed).

Chou, Wu, Yang, Shen, Yang: "Effect of Advanced Glycation End Products on the Progression of Alzheimer's Disease." dans: Journal of Alzheimer's disease : JAD, Vol. 72, Issue 1, pp. 191-197, (2020) (PubMed).

Han, Ma, Zhu, Sun, Liu: "Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway." dans: Molecular and cellular endocrinology, Vol. 514, pp. 110878, (2020) (PubMed).

Pawlukianiec, Gryciuk, Mil, Żendzian-Piotrowska, Zalewska, Maciejczyk: "A New Insight into Meloxicam: Assessment of Antioxidant and Anti-Glycating Activity in In Vitro Studies." dans: Pharmaceuticals (Basel, Switzerland), Vol. 13, Issue 9, (2020) (PubMed).

Tang, Yu, Wu, Chen, Zeng, Wang, Yang, Mei, Cao, Qin: "Lychee seed extract protects against neuronal injury and improves cognitive function in rats with type II diabetes mellitus with cognitive impairment." dans: International journal of molecular medicine, Vol. 41, Issue 1, pp. 251-263, (2018) (PubMed).

Wang, Chen, Du, Long, Reed, Hu, Suppiramaniam, Hong, Tang: "Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice." dans: Neuropharmacology, Vol. 131, pp. 143-153, (2018) (PubMed).

Chen, Chen, Wu, Chou, Chen, Wei, Lee, Hong, Zheng, Chiu, Lin, Hsu, Hsu: "Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice." dans: Scientific reports, Vol. 7, pp. 40442, (2017) (PubMed).

Yang, Meng, Chen, Li, Cen, Wen, Zhang, Li: "Inhibition of Methylglyoxal-Induced AGEs/RAGE Expression Contributes to Dermal Protection by N-Acetyl-L-Cysteine." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 2, pp. 742-754, (2017) (PubMed).

Galiniak, Bartosz, Sadowska-Bartosz: "Glutathione is the main endogenous inhibitor of protein glycation." dans: General physiology and biophysics, Vol. 36, Issue 2, pp. 175-186, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à AGE

renin binding protein (RENBP), RBP, RNBP

Protein level used designations for AGE

  • AGE
  • GlcNAc 2-epimerase
  • N-acetyl-D-glucosamine 2-epimerase
  • N-acylglucosamine 2-epimerase
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