ALDH2 Produits
(Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
Catégories
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011].
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Catégories ALDH2 en vedette
ALDH2 Anticorps
High quality antibodies with extensive validation data.
ALDH2 Kits ELISA
Reliable ELISA kits for a wide range of species.
ALDH2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ALDH2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (8)
N° du produit
ABIN1724795
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (9)
N° du produit
ABIN3021779
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF, IHC (p), ICC
Validations
- (7)
N° du produit
ABIN2855041
Quantité
100 μL
Fiche technique
Fiche technique
ALDH2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953593
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953594
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964702
Quantité
96 tests
Fiche technique
Fiche technique
ALDH2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN666745
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN5569461
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344826
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ALDH2
: "Protein Phosphatase 2A Improves Cardiac Functional Response to Ischemia and Sepsis." dans: International journal of molecular sciences, Vol. 23, Issue 9, (2022) (PubMed).: "Imaging PARP with [18F]rucaparib in pancreatic cancer models." dans: European journal of nuclear medicine and molecular imaging, Vol. 49, Issue 11, pp. 3668-3678, (2022) (PubMed).
: "Fenofibrate -a PPARα agonist- increases alcohol dehydrogenase levels in the liver: implications for its possible use as an ethanol-aversive drug." dans: Adicciones, pp. 1226, (2019) (PubMed).
: "Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide." dans: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 5, pp. 595-601, (2017) (PubMed).
: "Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells." dans: Scientific reports, Vol. 6, pp. 23340, (2017) (PubMed).
: "Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid β-oxidation pathway in HepG2 cells." dans: Amino acids, Vol. 48, Issue 5, pp. 1297-307, (2017) (PubMed).
: "Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress." dans: Free radical biology & medicine, Vol. 93, pp. 165-76, (2016) (PubMed).
: "A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse." dans: Journal of Alzheimer's disease : JAD, Vol. 40, Issue 4, pp. 1039-53, (2014) (PubMed).
: "Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer." dans: Journal of proteome research, Vol. 12, Issue 8, pp. 3780-91, (2013) (PubMed).
: "Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease." dans: European heart journal, Vol. 33, Issue 13, pp. 1606-14, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à ALDH2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1), aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L), aldehyde dehydrogenase 2 family (mitochondrial) (aldh2), aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), aldehyde dehydrogenase 2 (aldh2), aldehyde dehydrogenase (RHA1_RS43090), aldehyde dehydrogenase (NAD(+)) (aldH2), hypothetical protein (OE_RS03015), aldehyde dehydrogenase (aldH2), aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2), aldehyde dehydrogenase 2, mitochondrial (Aldh2), Ahd-5, Ahd5, aldh-e2, ALDH-E2, aldh2, aldh2a, aldhi, ALDHI, aldm, ALDM, MGC80785, rf2b, zgc:63786Protein level used designations for ALDH2
- aldehyde dehydrogenase 2
- aldehyde dehydrogenase 2 family (mitochondrial)
- aldehyde dehydrogenase 2 family (mitochondrial)a
- aldehyde dehydrogenase 2.1
- mitochondrial aldehyde dehydrogenase 2
- ALDH2B6
- mitochondrial aldehyde dehydrogenase RF2B
- aldehyde dehydrogenase
- aldehyde dehydrogenase (NAD(+))
- ALDH class 2
- ALDH-E2
- aldehyde dehydrogenase, mitochondrial
- aldehyde dehydrogenase, mitochondrial-like
- acetaldehyde dehydrogenase 2
- liver mitochondrial ALDH
- nucleus-encoded mitochondrial aldehyde dehydrogenase 2
- ALDH1
- aldehyde dehydrogenase 2, mitochondrial
- mitochondrial aldehyde dehydrogenase
- ALDHI
- AHD-M1
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