Aminoacylase 1 Produits
(Aminoacylase 1 (ACY1))
Catégories
This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Nov 2010].
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Catégories Aminoacylase 1 en vedette
Aminoacylase 1 Anticorps
High quality antibodies with extensive validation data.
Aminoacylase 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Aminoacylase 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Aminoacylase 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IP, IHC (p)
Validations
- (1)
- (6)
N° du produit
ABIN559777
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7434791
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Mouse, Rat
Application
WB, IHC, FACS, IHC (p)
Validations
- (6)
N° du produit
ABIN1496452
Quantité
100 μL
Fiche technique
Fiche technique
Aminoacylase 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953660
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4881733
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730070
Quantité
96 tests
Fiche technique
Fiche technique
Aminoacylase 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121810
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121809
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305823
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Aminoacylase 1
: "Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers." dans: Journal of proteome research, Vol. 11, Issue 2, pp. 728-35, (2012) (PubMed).: "The molecular basis of aminoacylase 1 deficiency." dans: Biochimica et biophysica acta, Vol. 1812, Issue 6, pp. 685-90, (2011) (PubMed).
: "Acylase 1 expression in rat intestinal crypt--villus axis." dans: Cell biology international, Vol. 31, Issue 9, pp. 966-73, (2007) (PubMed).
: "Aminoacylase I deficiency: a novel inborn error of metabolism." dans: Biochemical and biophysical research communications, Vol. 338, Issue 3, pp. 1322-6, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à Aminoacylase 1
aminoacylase 1 (ACY1), aminoacylase 1 (acy1), aminoacylase 1, gene 1 S homeolog (acy1.1.S), aminoacylase 1, gene 1 (acy1.1), aminoacylase 1 (Acy1), 1110014J22Rik, ACY-1, Acy-1, acy1, ACY1, Acy1a, Acy1b, acy1d, ACY1D, acylase, si:zfos-226g1.1, zgc:55605, zgc:76955Protein level used designations for Aminoacylase 1
- aminoacylase-1
- aminoacylase 1
- N-acyl-L-amino-acid amidohydrolase
- acylase
- ACY IA
- ACY IB
- ACY-1A
- ACY-1B
- aminoacylase-1A
- aminoacylase-1B
- ACY-1
- N-acylamino acid aminohydrolase (Aminoacylase 1)
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