Aminoacylase 1 Protein (ACY1) (AA 1-408) (His tag)

N° du produit ABIN667808

Détail du produit

Antigène: Aminoacylase 1 (ACY1)

Type de proteíne: Recombinant

Attributs du protein: AA 1-408

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Aminoacylase 1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: ACY1, 1-408aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: Aminoacylase 1 (ACY1)

Autre désignation: ACY1 (ACY1 Produits)

Synonymes: si:zfos-226g1.1 Protein, zgc:55605 Protein, zgc:76955 Protein, acy1 Protein, acy1d Protein, acylase Protein, ACY1 Protein, ACY-1 Protein, ACY1D Protein, 1110014J22Rik Protein, Acy-1 Protein, Acy1a Protein, Acy1b Protein, aminoacylase 1 Protein, aminoacylase 1, gene 1 S homeolog Protein, aminoacylase 1, gene 1 Protein, ACY1 Protein, acy1 Protein, acy1.1.S Protein, acy1.1 Protein, Acy1 Protein

Sujet: Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids. Recombinant human ACY1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ACY1D, ACYLASE, Aminoacylase 1. NCBI no.: NP_000657

Poids moléculaire: 48.0kDa (428aa) confirmed by MALDI-TOF