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AMPK alpha Produits

(SNF1A/AMP-Activated Protein Kinase (SNF1A))
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].

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Catégories AMPK alpha en vedette

AMPK alpha Anticorps

High quality antibodies with extensive validation data.

AMPK alpha Kits ELISA

Reliable ELISA kits for a wide range of species.

AMPK alpha recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
  • (4)
N° du produit ABIN6255610
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
N° du produit ABIN7138633
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN391388
Quantité 400 μL
Fiche technique Fiche technique

AMPK alpha recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6971288
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971290
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971289
Quantité 96 tests
Fiche technique Fiche technique

Dernières publications sur nos produits AMPK alpha

Yuan, Xu, Jiang, Cai, Wang, Peng, Sun, Zhu, Zhang, Yue, He, Yang, Zeng, Du, Zhang, Ibrahimi, Schaul, Jiang, Wang, Sun, Wang, Liu, Wang, Wang, Zhu, Gao, Xi, Yin, Li, Xu, Zhang, Shu: "Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation." dans: The EMBO journal, Vol. 39, Issue 7, pp. e103304, (2020) (PubMed).

Li, Xiong, Xu, Duan, Yang, Zhou, Tu: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." dans: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).

Zhang, Xie, Wang, Zhang, Yang: "Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model." dans: Journal of cellular physiology, Vol. 233, Issue 6, pp. 4626-4633, (2018) (PubMed).

Xie, Huang, Tang, Ye, Yang, Guo, Tian, Xie, Peng, Xie: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." dans: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).

Li, Li, Zeng, Yang, Liu, Zhang, Song, Yao, Ma, Li, Wang, Wei: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." dans: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).

Arab Sadeghabadi, Nourbakhsh, Pasalar, Emamgholipour, Golestani, Larijani, Razzaghy-Azar: "Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance." dans: Obesity research & clinical practice, Vol. 12, Issue 2, pp. 167-173, (2018) (PubMed).

Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." dans: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

Koroglu, Tola, Temel Yuksel, Aslan Cetin, Turhan, Topcu, Dag: "Maternal serum AMP-activated protein kinase levels in mild and severe preeclampsia." dans: The journal of maternal-fetal & neonatal medicine, pp. 1-6, (2018) (PubMed).

Huang, Li, Xie, Ye, Chen, Song, Tang, Xie: "High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer." dans: Breast (Edinburgh, Scotland), Vol. 30, pp. 39-46, (2017) (PubMed).

Deng, Luo, Lai, Song, Peng, Wei: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." dans: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à AMPK alpha

protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2), AMPK, AMPK2, AMPKa2, PRKAA

Protein level used designations for AMPK alpha

  • 5'-AMP-activated protein kinase catalytic subunit alpha-2
  • 5'-AMP-activated protein kinase, catalytic alpha-2 chain
  • ACACA kinase
  • AMPK subunit alpha-2
  • AMPK-alpha-2 chain
  • HMGCR kinase
  • acetyl-CoA carboxylase kinase
  • hydroxymethylglutaryl-CoA reductase kinase
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