Amylin/DAP Produits
(Islet Amyloid Polypeptide (IAPP))
Catégories
Amylin, also known as islet amyloid polypeptide (IAPP), is a peptide hormone primarily produced by pancreatic beta cells. It plays several important roles in regulating glucose metabolism and satiety. Here are the major cellular mechanisms in which amylin is involved:
- Glucose Regulation and Delayed Absorption: Amylin helps regulate blood glucose levels by slowing down the emptying of the stomach, delaying glucose absorption, and reducing post-meal blood sugar spikes.
- Appetite Control and Satiety: Amylin acts in the brain to induce feelings of fullness and reduce food intake, contributing to appetite control and weight management.
- Inhibition of Glucagon and Insulin Sensitivity: Amylin inhibits glucagon secretion, helping to maintain glucose homeostasis, and may enhance insulin sensitivity in peripheral tissues, aiding in overall metabolic health.
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Catégories Amylin/DAP en vedette
Amylin/DAP Anticorps
High quality antibodies with extensive validation data.
Amylin/DAP Kits ELISA
Reliable ELISA kits for a wide range of species.
Amylin/DAP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Amylin/DAP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7426055
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6259921
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7157084
Quantité
100 μg
Fiche technique
Fiche technique
Amylin/DAP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957220
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968064
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968062
Quantité
96 tests
Fiche technique
Fiche technique
Amylin/DAP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123638
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1307318
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7392188
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Amylin/DAP
: "Hsp72 (HSPA1A) Prevents Human Islet Amyloid Polypeptide Aggregation and Toxicity: A New Approach for Type 2 Diabetes Treatment." dans: PLoS ONE, Vol. 11, Issue 3, pp. e0149409, (2016) (PubMed).: "Differential effect of amylin on endothelial-dependent vasodilation in mesenteric arteries from control and insulin resistant rats." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0120479, (2015) (PubMed).
: "The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0133263, (2015) (PubMed).
: "Rational design of potent domain antibody inhibitors of amyloid fibril assembly." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 19965-70, (2012) (PubMed).
: "Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway." dans: The American journal of pathology, Vol. 176, Issue 2, pp. 861-9, (2010) (PubMed).
: "Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition." dans: Pancreas, Vol. 39, Issue 6, pp. 843-6, (2010) (PubMed).
: "Serum levels of proamylin and amylin in normal subjects and patients with impaired glucose regulation and type 2 diabetes mellitus." dans: Acta diabetologica, Vol. 47, Issue 3, pp. 265-70, (2010) (PubMed).
: "Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey." dans: Veterinary pathology, Vol. 45, Issue 1, pp. 67-72, (2008) (PubMed).
: "Amyloid oligomers in diabetic and nondiabetic human pancreas." dans: Translational research : the journal of laboratory and clinical medicine, Vol. 153, Issue 1, pp. 24-32, (2008) (PubMed).
: "Cloning and expression of human islet amyloid polypeptide in cultured cells." dans: Biochemical and biophysical research communications, Vol. 356, Issue 3, pp. 622-8, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à Amylin/DAP
islet amyloid polypeptide (IAPP), islet amyloid polypeptide (Iapp), Amylin, DAP, IAP, LOC100230121Protein level used designations for Amylin/DAP
- Islet amyloid polypeptide (diabetes-associated peptide; amylin)
- amylin
- diabetes-associated peptide
- insulinoma amyloid peptide
- DAP
- islet amyloid polypeptide
- amyloid protein
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