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ANAPC5 Produits

(Anaphase Promoting Complex Subunit 5 (ANAPC5))

Catégories

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008].

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Catégories ANAPC5 en vedette

ANAPC5 Anticorps

High quality antibodies with extensive validation data.

ANAPC5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ANAPC5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (8)
N° du produit ABIN950136
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP
Validations
  • (5)
N° du produit ABIN6136867
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN7144073
Quantité 100 μL
Fiche technique Fiche technique

ANAPC5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345038
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3136268
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3089043
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ANAPC5

Fehr, Gualberto, Savaryn, Terhune, Yu: "Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a." dans: PLoS pathogens, Vol. 8, Issue 7, pp. e1002789, (2012) (PubMed).

Tran, Kamil, Coen, Spector et al.: "Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated ..." dans: Journal of virology, Vol. 84, Issue 20, pp. 10832-43, (2010) (PubMed).

Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: "The full-ORF clone resource of the German cDNA Consortium." dans: BMC genomics, Vol. 8, pp. 399, (2008) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).

Kraft, Herzog, Gieffers, Mechtler, Hagting, Pines, Peters: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." dans: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, (2003) (PubMed).

Yu, Peters, King, Page, Hieter, Kirschner: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." dans: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, (1998) (PubMed).

Synonymes et noms alternatifs relatifs à ANAPC5

anaphase promoting complex subunit 5 (ANAPC5), anaphase promoting complex subunit 5 (anapc5), anaphase-promoting complex subunit 5 (LOC100093215), anaphase promoting complex subunit 5 L homeolog (anapc5.L), anaphase-promoting complex subunit 5 (Anapc5), anaphase-promoting complex subunit (AT1G06590), anaphase-promoting complex subunit Apc5 (apc5), anaphase promoting complex subunit 5 (Anapc5), 2510006G12Rik, AA408751, AA536819, AA986414, ANAPC5, Anpc5, APC5, DDBDRAFT_0206386, DDBDRAFT_0234269, DDB_0206386, DDB_0234269, F12K11.7, F12K11_7, MGC89697, wu:fb75a09, zgc:55800

Protein level used designations for ANAPC5

  • anaphase-promoting complex subunit 5
  • cyclosome subunit 5
  • APC5
  • anaphase promoting complex subunit 5
  • anaphase-promoting complex subunit 5-like
  • 20S cyclosome/APC complex protein apc5
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