IDO2 anticorps

N° du produit ABIN1043821

N° du produit (Fournisseur): 210-301-e59

Cet anticorps Souris Monoclonal détecte spécifiquement IDO2 dans WB, ELISA et FM. Il présente une réactivité envers Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour IDO2 anticorps (ABIN1043821)

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Clone: 1HC

Détail du produit anti-IDO2 anticorps

N° du produit (Fournisseur): 210-301-e59

Fournisseur: Rockland

Fonction: IDO2 Antibody

Réactivité croisée (Details): IDO2 antibody is specific for mouse IDO2 protein.

Attributs du produit: Synonyms: mouse anti-IDO2 Antibody, Indoleamine 2,3-dioxygenase 2, Indol1, Indoleamine 2,3-dioxygenase-like protein 1, Indoleamine-pyrrole 2,3-dioxygenase-like protein 1, Ido-2, Ido 2, IDO2 antibody, mouse anti-IDO-2 antibody

Purification: Anti-IDO2 was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Anti-IDO2 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with complete mouse IDO2 protein followed by hybridoma development.

Immunogen Type: Recombinant Protein

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Application Note: Anti-IDO2 antibody has been tested in western blot and is suitable for use in ELISA and IF. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1:500-1:1500

ELISA Dilution: 1:5000 - 1:50000

IF Microscopy Dilution: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-IDO2 (ABIN1043821)

Wolff, Driever, Erdlenbruch, Kortmann, Rutkowski, Pietsch, Parker, Metz, Gnekow, Kramm: "Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol." dans: Cancer, Vol. 116, Issue 3, pp. 705-12, (2010) (PubMed).

Metz, Duhadaway, Rust, Munn, Muller, Mautino, Prendergast: "Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase." dans: Molecular cancer therapeutics, Vol. 9, Issue 6, pp. 1864-71, (2010) (PubMed).

Détails sur IDO2

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Autre désignation: Ido2

Sujet: Background: Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1, and may play a role in T and B Cell Immunity. IDO2's role in immune regulation will be become clearer following the completion of genetic knock-out studies. IDO2 is expressed in a few select cell types and levels of protein expression appear to be very low, perhaps below the level of detection by IHC. Small-molecule inhibitors of indoleamine 2,3-dioxygenase (IDO) are currently being translated to clinic for evaluation as cancer therapeutics.

ID gène: 209176

NCBI Accession: NP_666061

UniProt: Q8R0V5