Major Capsid Protein L1 anticorps

N° du produit ABIN1045681

Cet anticorps Lapin Polyclonal détecte spécifiquement Major Capsid Protein L1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Human Papillomavirus (HPV).

Aperçu rapide pour Major Capsid Protein L1 anticorps (ABIN1045681)

Antigène: Major Capsid Protein L1

Reactivité: Human Papillomavirus (HPV)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogène: Recombinant HPV18 Major capsid protein L1 protein

Isotype: IgG

Information d'application

Indications d'application: Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: -20 °C

Stockage commentaire: Shipped at 4 °C. Upon delivery aliquot and store at -20 °C or -80 °C.

Détail du antigène

Antigène: Major Capsid Protein L1

Classe de substances: Viral Protein

Sujet: Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Synonyms: L1

UniProt: P06794