PSME3 anticorps (AA 2-252) (FITC)

N° du produit ABIN1045992

Cet anticorps anti-PSME3 est un anticorps Lapin Polyclonal détectant PSME3 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour PSME3 anticorps (AA 2-252) (FITC) (ABIN1045992)

Antigène: PSME3

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSME3 est conjugé à/à la FITC

Application: Western Blotting (WB), ELISA

Détail du produit anti-PSME3 anticorps (FITC)

Épitope: AA 2-252

Fonction: PSME3 Antibody, FITC conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Proteasome activator complex subunit 3 protein (2-252AA)

Isotype: IgG

Information d'application

Indications d'application: Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PSME3

Antigène: PSME3

Autre désignation: PSME3

Sujet:

Background: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.

Aliases: 11S regulator complex gamma subunit antibody, 11S regulator complex subunit gamma antibody, Activator of multicatalytic protease subunit 3 antibody, Ki antibody, Ki antigen antibody, Ki nuclear autoantigen antibody, Ki, PA28 gamma antibody, PA28 gamma antibody, PA28g antibody, PA28gamma antibody, Proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody, Proteasome (prosome, macropain) activator subunit 3 antibody, Proteasome activator 28 gamma antibody, Proteasome activator 28 subunit gamma antibody, Proteasome activator complex subunit 3 antibody, Proteasome activator subunit 3 antibody, PSME3 antibody, PSME3_HUMAN antibody, REG GAMMA antibody, REG-gamma antibody

UniProt: P61289

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA