CMPK2 anticorps (C-Term)

N° du produit ABIN1077386

L’anticorps Lapin Polyclonal anti-CMPK2 a été validé pour WB, ELISA et IF. Il convient pour détecter CMPK2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CMPK2 anticorps (C-Term) (ABIN1077386)

Antigène: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMPK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-CMPK2 anticorps

Épitope: C-Term

Specificité: Multiple isoforms of CMPK2 are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogène: CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2.

Isotype: IgG

Information d'application

Indications d'application: CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(CT) Cytidine monophosphate (UMP-CMP) kinase 2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: CMPK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur CMPK2

Antigène: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Autre désignation: CMPK2

Sujet: UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
Synonyms: Cytidine monophosphate (UMP-CMP) kinase 2, TMPK2, TYKi, UMP-CMPK2

Poids moléculaire: 49 kDa

ID gène: 129607

NCBI Accession: NP_997198

Pathways: Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin