CMPK2 anticorps (C-Term)

N° du produit ABIN6991766

Détail du produit anti-CMPK2 anticorps

Antigène: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Épitope: AA 370-420, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMPK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Multiple isoforms of CMPK2 are known to exist.

Purification: CMPK2 Antibody is affinity chromatography purified via peptide column.

Immunogène: CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2. The immunogen is located within amino acids 370 - 420 of CMPK2.

Isotype: IgG

Information d'application

Indications d'application: CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CMPK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CMPK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CMPK2

Antigène: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Autre désignation: CMPK2 (CMPK2 Produits)

Synonymes: anticorps si:ch211-276e8.3, anticorps TMPK2, anticorps TYKi, anticorps UMP-CMPK2, anticorps 1200004E04Rik, anticorps TDKI, anticorps Tyki, anticorps cytidine/uridine monophosphate kinase 2, anticorps cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial, anticorps CMPK2, anticorps cmpk2, anticorps Cmpk2

Sujet: CMPK2 Antibody: UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response

Poids moléculaire: 49 kDa

ID gène: 129607

NCBI Accession: NP_997198

UniProt: Q5EBM0

Pathways: Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin