TPT1 anticorps

N° du produit ABIN1077430

Cet anticorps Lapin Monoclonal détecte spécifiquement TPT1 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TPT1 anticorps (ABIN1077430)

Antigène: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TPT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TPT1 anticorps

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.

Isotype: IgG

Information d'application

Indications d'application: TPT1 antibody can be used for detection of TPT1 by Western blot at 0.5 - 1 μg/mL.

Commentaires:

(IN) Translationally-controlled tumor protein 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: TPT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur TPT1

Antigène: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Autre désignation: TPT1

Sujet: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
Synonyms: Tumor protein translationally-controlled 1, translationally-controlled tumor protein, TCTP, fortilin, histamine-releasing factor, HRF, p23

Poids moléculaire: 19 kDa (calculated)

ID gène: 7178

NCBI Accession: NP_003286

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling