IL-15 anticorps

N° du produit ABIN1077441

Détail du produit anti-IL-15 anticorps

Antigène: IL-15 (IL15) (Interleukin 15 (IL15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-15 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: At least two isoforms of IL-15 are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15.

Isotype: IgG

Information d'application

Indications d'application: IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 μg/mL.

Commentaires:

(IN) Interleukin-15

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Détails sur IL-15

Antigène: IL-15 (IL15) (Interleukin 15 (IL15))

Autre désignation: IL15 (IL15 Produits)

Synonymes: anticorps IL15, anticorps AI503618, anticorps IL-15, anticorps interleukin 15, anticorps IL15, anticorps Il15

Sujet: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Synonyms: Interleukin-15, IL15

Poids moléculaire: 18 kDa

ID gène: 3600

NCBI Accession: NP_000576

Pathways: Signalistation JAK/STAT, Glycosaminoglycan Metabolic Process