PLK1 anticorps (AA 331-508)

N° du produit ABIN1098105

Cet anticorps anti-PLK1 est un anticorps Souris Monoclonal détectant PLK1 dans WB, ELISA, IHC et FACS. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour PLK1 anticorps (AA 331-508) (ABIN1098105)

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 3C11

Détail du produit anti-PLK1 anticorps

Épitope: AA 331-508

Fonction: PLK1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PLK1 (AA: 331-508) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PLK1 (ABIN1098105)

Lin, Sun, Wang: "Suppression of Polo like kinase 1 (PLK1) by p21(Waf1) mediates the p53-dependent prevention of caspase-independent mitotic death." dans: Cellular signalling, Vol. 23, Issue 11, pp. 1816-23, (2011) (PubMed).

Yoshioka, Kimura, Saio, Era, Okano: "Plk1 is negatively regulated by RNF8." dans: Biochemical and biophysical research communications, Vol. 410, Issue 1, pp. 57-61, (2011) (PubMed).

Susilowati, Okamura, Hirota, Shono, Yoshida, Murakami, Tabata, Nagamune, Haneji, Miyake: "Intermedilysin induces EGR-1 expression through calcineurin/NFAT pathway in human cholangiocellular carcinoma cells." dans: Biochemical and biophysical research communications, Vol. 404, Issue 1, pp. 57-61, (2011) (PubMed).

Détails sur PLK1

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Autre désignation: PLK1

Sujet: Polo-like kinase 1 (Plk1) plays key roles in many aspects of mitosis. Suppression of Plk1 by p21(Waf1) is responsible for p53-dependent protection against adriamycin-induced caspase-independent mitotic death.

Poids moléculaire: 68 kDa

ID gène: 5347

UniProt: P53350

Pathways: Cycle Cellulaire, M Phase