IGF2 anticorps (AA 25-180)

N° du produit ABIN1098108

Détail du produit anti-IGF2 anticorps

Antigène: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Épitope: AA 25-180

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human IGF2 (AA: 25-180) expressed in E. coli.

Clone: 8H1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-IGF2 (ABIN1098108)

El Tayebi, Salah, El Sayed, Salam, Zekri, Zayed, Salem, Esmat, Abdelaziz: "Expression of insulin-like growth factor-II, matrix metalloproteinases, and their tissue inhibitors as predictive markers in the peripheral blood of HCC patients." dans: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 16, Issue 4, pp. 346-54, (2011) (PubMed).

Shetty, Movva, Pasupuleti, Vedicherlla, Vattam, Venkatasubramanian, Ahuja, Hasan: "Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer." dans: Journal of cancer research and clinical oncology, Vol. 137, Issue 2, pp. 339-45, (2011) (PubMed).

Détails sur IGF2

Antigène: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Autre désignation: IGF2 (IGF2 Produits)

Sujet:

Description: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases: IGF-II, PP9974, C11orf43, FLJ22066, FLJ44734

Poids moléculaire: 20.1 kDa

ID gène: 3481

HGNC: 3481

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation