CSNK2A2 anticorps (AA 194-350)

N° du produit ABIN1098114

Détail du produit anti-CSNK2A2 anticorps

Antigène: CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

Épitope: AA 194-350

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CSNK2A2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. coli.

Clone: 1-00E-01

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-CSNK2A2 (ABIN1098114)

Chemnitz, Pieper, Grüttner, Hauber: "Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression." dans: European journal of immunology, Vol. 39, Issue 1, pp. 267-79, (2009) (PubMed).

Schäfer, Götz, Dudek, Hessenauer, Matti, Montenarh: "KIF5C: a new binding partner for protein kinase CK2 with a preference for the CK2alpha' subunit." dans: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 2, pp. 339-49, (2009) (PubMed).

Détails sur CSNK2A2

Antigène: CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

Autre désignation: CSNK2A2 (CSNK2A2 Produits)

Synonymes: anticorps CK2A2, anticorps CSNK2A1, anticorps 1110035J23Rik, anticorps C77789, anticorps CK2, anticorps CSNK2A2, anticorps ck2a2, anticorps csnk2a1, anticorps wu:fi09h12, anticorps casein kinase 2 alpha 2, anticorps casein kinase 2, alpha prime polypeptide, anticorps casein kinase 2 alpha 2 L homeolog, anticorps casein kinase 2, alpha prime polypeptide a, anticorps CSNK2A2, anticorps Csnk2a2, anticorps csnk2a2.L, anticorps csnk2a2, anticorps csnk2a2a

Sujet:

Description: Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.

Aliases: CK2A2, CSNK2A1, FLJ43934

Poids moléculaire: 41.2 kDa

ID gène: 1459

HGNC: 1459

Pathways: SARS-CoV-2 Protein Interactome