LMO2 anticorps (AA 1-158)

N° du produit ABIN1098128

L’anticorps Souris Monoclonal anti-LMO2 a été validé pour ELISA et FACS. Il convient pour détecter LMO2 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour LMO2 anticorps (AA 1-158) (ABIN1098128)

Antigène: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LMO2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 4D8

Détail du produit anti-LMO2 anticorps

Épitope: AA 1-158

Fonction: LMO2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-LMO2 (ABIN1098128)

Cubedo, Maurin, Jiang, Lossos, Wright: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." dans: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).

Baecklund, Backlin, Mansouri, Klareskog, Askling, Iliadou, Enblad, Lossos, Natkunam, Rosenquist: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." dans: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).

Détails sur LMO2

Antigène: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Autre désignation: LMO2

Sujet: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 18.4 kDa

UniProt: P25791

Pathways: Chromatin Binding