T Antigen (AA 257-309) anticorps

N° du produit ABIN1098136

Cet anticorps Souris Monoclonal détecte spécifiquement T Antigen dans FACS et IHC. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour T Antigen (AA 257-309) anticorps (ABIN1098136)

Antigène: T Antigen

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: 1H9A2

Détail du produit

Épitope: AA 257-309

Purification: Purified

Immunogène: Purified recombinant fragment of human T (AA: 257-309 ) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Référence

Shen, Li, Yang, Lu, Zou, Wang, Deng: "Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3." dans: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, Vol. 18, Issue 1, pp. 96-9, (2010) (PubMed).

Tirabosco, Mangham, Rosenberg, Vujovic, Bousdras, Pizzolitto, De Maglio, den Bakker, Di Francesco, Kalil, Athanasou, ODonnell, McCarthy, Flanagan: "Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue." dans: The American journal of surgical pathology, Vol. 32, Issue 4, pp. 572-80, (2008) (PubMed).

Détail du antigène

Antigène: T Antigen

Sujet: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

Poids moléculaire: 47.4kDa

ID gène: 6862

HGNC: 6862

UniProt: O15178