DKK3 anticorps (AA 91-350)

N° du produit ABIN1098142

Cet anticorps Souris Monoclonal détecte spécifiquement DKK3 dans ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour DKK3 anticorps (AA 91-350) (ABIN1098142)

Antigène: DKK3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DKK3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 8A5C6

Détail du produit anti-DKK3 anticorps

Épitope: AA 91-350

Fonction: DKK3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DKK3 (AA: 91-350 ) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-DKK3 (ABIN1098142)

Du, Kataoka, Sakaguchi, Abarzua, Than, Sonegawa, Makino, Shimizu, Huh: "Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis." dans: Experimental dermatology, Vol. 20, Issue 3, pp. 273-7, (2011) (PubMed).

Medinger, Tzankov, Kern, Pircher, Hermann, Ott, Gastl, Untergasser, Gunsilius: "Increased Dkk3 protein expression in platelets and megakaryocytes of patients with myeloproliferative neoplasms." dans: Thrombosis and haemostasis, Vol. 105, Issue 1, pp. 72-80, (2011) (PubMed).

Détails sur DKK3

Antigène: DKK3

Sujet: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

Poids moléculaire: 38.3 kDa

ID gène: 27122

UniProt: Q9UBP4