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MMP2 anticorps (AA 242-396)

MMP2 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 4D1E2 unconjugated
N° du produit ABIN1098146
  • Antigène Voir toutes MMP2 Anticorps
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Épitope
    • 16
    • 16
    • 16
    • 11
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-396
    Reactivité
    • 151
    • 80
    • 65
    • 49
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 125
    • 41
    • 1
    Souris
    Clonalité
    • 122
    • 45
    Monoclonal
    Conjugué
    • 80
    • 14
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MMP2 est non-conjugé
    Application
    • 135
    • 58
    • 52
    • 39
    • 39
    • 37
    • 31
    • 29
    • 18
    • 15
    • 14
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human MMP2 (AA: 242-396) expressed in E. coli.
    Clone
    4D1E2
    Isotype
    IgG1
    Top Product
    Discover our top product MMP2 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Langers, Verspaget, Hawinkels, Kubben, van Duijn, van der Reijden, Hardwick, Hommes, Sier: "MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients." dans: British journal of cancer, Vol. 106, Issue 9, pp. 1495-8, (2012) (PubMed).

    Hajighasemi: "Profiles of MMP-2 expression in Jurkat, Molt-4 and U937 cells." dans: Iranian journal of immunology : IJI, Vol. 8, Issue 2, pp. 120-6, (2011) (PubMed).

  • Antigène
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Autre désignation
    MMP2 (MMP2 Produits)
    Synonymes
    anticorps 2-MMP, anticorps CG1794, anticorps DM2-MMP, anticorps Dm2-MMP, anticorps Dmel\\CG1794, anticorps MMP2, anticorps anon-WO0118547.84, anticorps dm-2MMP, anticorps dmmp2, anticorps l(2)02353, anticorps mmp2, anticorps wu:fa99h12, anticorps wu:fk89d01, anticorps fgmmp-2, anticorps Mmp-2, anticorps LOC100135793, anticorps Clg4a, anticorps GelA, anticorps MMP-2, anticorps CLG4, anticorps CLG4A, anticorps MMP-II, anticorps MONA, anticorps TBE-1, anticorps matrix metallopeptidase 2, anticorps Matrix metalloproteinase 2, anticorps matrix metalloproteinase 2, anticorps matrix metalloproteinase-2, anticorps MMP2, anticorps Mmp2, anticorps mmp2, anticorps LOC657982, anticorps LOC100135793
    Sujet

    Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. , ,

    Aliases: CLG4, MONA, CLG4A, TBE-1, MMP-II

    Poids moléculaire
    73.8 kDa
    ID gène
    4313
    HGNC
    4313
    Pathways
    Activation of Innate immune Response
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