MMP2 anticorps (AA 444-575)

N° du produit ABIN6940067

L’anticorps anti-MMP2 Monoclonal Souris est utilisé pour la détection de MMP2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MMP2 anticorps (AA 444-575) (ABIN6940067)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB)

Clone: MMP2-1501

Détail du produit anti-MMP2 anticorps

Épitope: AA 444-575

Fonction: MMP2 / Collagenase Type IV A (Tumor Metastasis Marker) Antibody

Specificité: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Positive Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

Known Application: Western Blot (0.5-1 μg/mL) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2

Sujet:

72kD type IV collagenase, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metalloproteinase-2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE-1

U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

Poids moléculaire: 72kDa (Pro), 63kDa (cleaved)

ID gène: 4313, 513617

UniProt: P08253

Pathways: Activation of Innate immune Response