Osteopontin anticorps (AA 167-314)

N° du produit ABIN1098149

L’anticorps Souris Monoclonal anti-Osteopontin a été validé pour ELISA, IHC et ICC. Il convient pour détecter Osteopontin dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour Osteopontin anticorps (AA 167-314) (ABIN1098149)

Antigène: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Osteopontin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 7C5H12

Détail du produit anti-Osteopontin anticorps

Épitope: AA 167-314

Fonction: SPP1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Osteopontin (ABIN1098149)

Liersch, Gerss, Schliemann, Bayer, Schwöppe, Biermann, Appelmann, Kessler, Löwenberg, Büchner, Hiddemann, Müller-Tidow, Berdel, Mesters: "Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients." dans: Blood, Vol. 119, Issue 22, pp. 5215-20, (2012) (PubMed).

Wang, Wang, Tang: "Osteopontin expression in nasopharyngeal carcinoma: its relevance to the clinical stage of the disease." dans: Journal of cancer research and therapeutics, Vol. 7, Issue 2, pp. 138-42, (2011) (PubMed).

Détails sur Osteopontin

Antigène: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Autre désignation: SPP1

Sujet: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 35.4 kDa

ID gène: 6696

UniProt: P10451

Pathways: Regulation of Cell Size