ARID4A anticorps (C-Term)
Aperçu rapide pour ARID4A anticorps (C-Term) (ABIN1105440)
Antigène
Voir toutes ARID4A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- NSSKCTPVKH LNVSKPQKLA RSPARISPHI KDGEKDKHRE KHPNSSPRTY
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Réactivité croisée (Details)
- Species reactivity (expected):Dog, Mouse, Rat, Bovine, ChickenSpecies reactivity (tested):Human
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Purification
- Purified using Protein A affinity column
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Immunogène
- The immunogen for anti-ARID4A antibody: synthetic peptide directed towards the C terminal of human ARID4A.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Add 100 μL of distilled water to a final concentration of 1 mg/mL.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))
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Autre désignation
- ARID4A
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Sujet
- ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.Synonyms: ARID domain-containing protein 4A, AT-rich interactive domain-containing protein 4A, RBBP-1, RBBP1, RBP1, Retinoblastoma-binding protein 1
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ID gène
- 5926
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NCBI Accession
- NP_002883
Antigène
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