Hexosaminidase A anticorps

N° du produit ABIN1105521

Cet anticorps anti-Hexosaminidase A est un anticorps Souris Monoclonal détectant Hexosaminidase A dans WB, FACS et EIA. Adapté pour Humain.

Aperçu rapide pour Hexosaminidase A anticorps (ABIN1105521)

Antigène: Hexosaminidase A (HEXA)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hexosaminidase A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: 3F10

Détail du produit anti-Hexosaminidase A anticorps

Specificité: Recognizes Beta-hexosaminidase alpha / HEXA

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur Hexosaminidase A

Antigène: Hexosaminidase A (HEXA)

Autre désignation: beta-Hexosaminidase alpha / HEXA

Sujet: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).Synonyms: Beta-N-acetylhexosaminidase subunit alpha, N-acetyl-beta-glucosaminidase subunit alpha

Poids moléculaire: 60.7 kDa

ID gène: 3073

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process