Syndecan 1 anticorps

N° du produit ABIN1105859

L’anticorps Souris Monoclonal anti-Syndecan 1 a été validé pour FACS, IHC (p) et IHC (fro). Il convient pour détecter Syndecan 1 dans des échantillons de Humain.

Aperçu rapide pour Syndecan 1 anticorps (ABIN1105859)

Antigène: Syndecan 1 (SDC1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syndecan 1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: B-A38

Détail du produit anti-Syndecan 1 anticorps

Specificité: The antibody B-A38 recognizes CD138 (Syndecan-1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Azide Free PBS, pH 7.4, 0.2 μm filter sterilized, None

Agent conservateur: Azide free

Détails sur Syndecan 1

Antigène: Syndecan 1 (SDC1)

Autre désignation: CD138 / Syndecan-1

Sujet: CD138 (syndecan-1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.Synonyms: SDC, SDC1, SYND1

ID gène: 6382

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism