CCR3 anticorps (FITC)

N° du produit ABIN1105990

Cet anticorps Souris Monoclonal détecte spécifiquement CCR3 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CCR3 anticorps (FITC) (ABIN1105990)

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR3 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: 444-11

Détail du produit anti-CCR3 anticorps (FITC)

Specificité: This antibody reacts with CD193 antigen. The antibody has also been reported to inhibit chemotactic migration of monocyte-derived DCs to RANTES (Ref.4). It suppresses the capacity of monocyte-derived DCs to stimulate allogenetic TCs proliferation and TCs derived IFN-γ secretion( Ref.4).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogène: Human CCR3 expressing transfectant (mouse pre-B cell lymphoma B300-19)

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 tests in 1 mLvolume of 10 μM NaPB, 0.09 % NaN3, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur CCR3

Antigène: CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

Autre désignation: CD193 / CCR3

Sujet: Dendritic cells (DCs) are major antigen presenting cells (APCs) capable of stimulation resting T cells (TCs) in the primary immune response and are more potent APCs than peripheral blood monocytes or B cells. Several CC and CXC chemokines receptors were found to be expressed on some DCs and these molecules have been implicated to mediate in part the trafficking of DCs from blood to tissues and then to lymph nodes, where they form a close association with TCs in the process of antigen presentation. Recent studies have shown that CD191/CCR1 and CD193/CCR3 are potentially involved in antigen-presenting cell function of human DCs.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor

ID gène: 1232

NCBI Accession: NP_001828

UniProt: P51677