CDK2 anticorps

N° du produit ABIN1106646

Cet anticorps anti-CDK2 est un anticorps Souris Monoclonal détectant CDK2 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CDK2 anticorps (ABIN1106646)

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK2 est non-conjugé

Application: Western Blotting (WB)

Clone: 8A12

Détail du produit anti-CDK2 anticorps

Specificité: This antibody recognizes human Cdk2 and human Cdk5 and does not recognize human Cdc2 (Cdk1) on Western blot.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Protein A agarose

Immunogène: Recombinant human Cdk2

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Prepare a stock solution by dissolving the lyophilized antibody 100 μL of distilled water. After reconstitution, the IgG concentration should be 1 mg/mL.

Buffer: PBS ( pH 7.2) containing 1 % sucrose, 0.09 % NaN3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Détails sur CDK2

Antigène: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Autre désignation: CDK2

Sujet: Cellular proliferation is controlled by a family of protein kinases in which the catalytic subunits are members of the cyclin-dependent kinase (cdk) family and the regulatory subunits are cyclins. To date, nine distinct Cdks in addition to eight different cyclins have been identified, in which different CDK/cyclin combinations serve to regulate distinct points in the mammalian cell division cycle. Although Cdc2Hs (Cdk1)/cyclin B controls the transition of cells from the G2 to M-phase, the activities of Cdk2/cyclin E and Cdk2/cyclin A are critical for G1/S-phase transition and progression through S-phase.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase

ID gène: 1017

NCBI Accession: NP_001789

UniProt: P24941

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA