Chips (N-Term) anticorps

N° du produit ABIN1106679

Cet anticorps anti- est un anticorps Souris Monoclonal détectant dans IHC (p), WB, IHC (fro), Func et EIA. Adapté pour Mammifères.

Aperçu rapide pour Chips (N-Term) anticorps (ABIN1106679)

Antigène: Chips

Reactivité: Mammifères

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: JNC1

Détail du produit

Épitope: N-Term

Specificité: This antibody detects reacts the N-terminus of CHIPS.

Purification: Protein G purified

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.01 % sodium azide, 0.1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 2-8 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Détail du antigène

Antigène: Chips

Sujet: The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of Staphylococcus aureus). CHIPS is a protein produced by Staphylococcus aureus that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. CHIPS and antibodies against CHIPS can be useful for various experimental infection models of Staphylococcus aureus. Furthermore these reagents can be of help in studies on the role of FPR and C5a in inflammatory processes.

ID gène: 2861356

NCBI Accession: YP_041409

UniProt: Q6GFB3