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ENO2/NSE anticorps

Cet anticorps anti-ENO2/NSE est un anticorps Souris Monoclonal détectant ENO2/NSE dans WB, IHC (p) et EIA. Adapté pour Humain.
N° du produit ABIN110682

Aperçu rapide pour ENO2/NSE anticorps (ABIN110682)

Antigène

Voir toutes ENO2/NSE (ENO2) Anticorps
ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Reactivité

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Humain

Hôte

  • 112
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Souris

Clonalité

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Monoclonal

Conjugué

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Cet anticorp ENO2/NSE est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone

1C1
  • Specificité

    This antibody reacts with a 45 kDa band corresponding to NSE on immunoblots of human brain extracts. We recommend the use of BM150 as the capture antibody in a sandwich ELISA with BM021.

    Purification

    Affinity chromatography on Protein G

    Immunogène

    Native, from brain

    Isotype

    IgG2a
  • Indications d'application

    ELISA. Western Blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

    Autre désignation

    Neuron Specific Enolase

    Sujet

    Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.Synonyms: 2-phospho-D-glycerate hydro-lyase, ENO2, Enolase 2, Gamma-enolase, NSE, Neural enolase

    ID gène

    2026

    NCBI Accession

    NP_001966

    UniProt

    P09104
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