Desmin anticorps

N° du produit ABIN1106975

L’anticorps Souris Monoclonal anti-Desmin a été validé pour WB, IF et IHC (fro). Il convient pour détecter Desmin dans des échantillons de Humain, Rat, Souris, Poulet, Hamster, Porc, Chien, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Desmin anticorps (ABIN1106975)

Antigène: Desmin (DES)

Reactivité: Humain, Rat, Souris, Poulet, Hamster, Porc, Chien, Lapin, Poisson zèbre (Danio rerio)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: RD301

Détail du produit anti-Desmin anticorps

Purification: Purified

Immunogène: Cytoskeletal desmin extract of chicken gizzard.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS with 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the lyophilized antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. store the reconstituted antibody at -20 °C.

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet: Desmin (53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.Synonyms: DES

ID gène: 9031

UniProt: P02542