Dystrophin anticorps

N° du produit ABIN1107040

Détail du produit anti-Dystrophin anticorps

Antigène: Dystrophin (DMD)

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dystrophin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody reacts to Dystrophin.

Purification: Affinity chromatography

Immunogène: Recombinant human dystrophin fragment.

Clone: DYS-48

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Dystrophin

Antigène: Dystrophin (DMD)

Autre désignation: Dystrophin / DMD (DMD Produits)

Synonymes: anticorps DMD, anticorps Dmd, anticorps MGC83347, anticorps DKFZp459C1629, anticorps dmd, anticorps MGC79631, anticorps DKFZp468A1620, anticorps Dp71, anticorps cb664, anticorps zfDYS, anticorps im:6911785, anticorps zgc:110165, anticorps BMD, anticorps CMD3B, anticorps DXS142, anticorps DXS164, anticorps DXS206, anticorps DXS230, anticorps DXS239, anticorps DXS268, anticorps DXS269, anticorps DXS270, anticorps DXS272, anticorps DXSmh7, anticorps DXSmh9, anticorps Dp427, anticorps dys, anticorps mdx, anticorps pke, anticorps DNADMD1, anticorps RATDMD, anticorps CG17750, anticorps CG31175, anticorps CG34157, anticorps CG7240, anticorps CG7243, anticorps CG7344, anticorps DLP, anticorps DLP1, anticorps DLP186, anticorps DLP2, anticorps DLP3, anticorps DmDLP, anticorps DmDYS, anticorps Dmel\\CG34157, anticorps Dp117, anticorps Dp186, anticorps Dp205, anticorps GI3046716, anticorps IDLP, anticorps det, anticorps dmDLP, anticorps dmDp186, anticorps dmDys, anticorps dystrophin, anticorps dystrophin, gene 1 L homeolog, anticorps dystrophin, gene 1, anticorps dystrophin, muscular dystrophy, anticorps Dystrophin, anticorps DMD, anticorps LOC708073, anticorps dmd.1.L, anticorps LOC465557, anticorps dmd.1, anticorps dmd, anticorps Dmd, anticorps Dys

Sujet: Dystrophin(DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons, the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.over expression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.

ID gène: 1756

NCBI Accession: NP_000100

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development