IFNA2 anticorps
Aperçu rapide pour IFNA2 anticorps (ABIN1107639)
Antigène
Voir toutes IFNA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts to IFN-alpha (II).
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Immunogène
- A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0,1 mg/mL
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Buffer
- PBS, 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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Autre désignation
- IFNA2 / Interferon alpha-2
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Sujet
- The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalppha family has over .. genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types. N39 is specific for INFalpha(II) and does not crossreact with INFalpha(I).Synonyms: IFN-alpha 2, Interferon alpha-A, LeIF A
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ID gène
- 3440
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NCBI Accession
- NP_000596
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UniProt
- P01563
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Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
Antigène
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