IL12B anticorps

N° du produit ABIN1107794

Détail du produit anti-IL12B anticorps

Antigène: IL12B (Interleukin 12 beta (IL12B))

Reactivité: Humain, Mouton, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL12B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Functional Studies (Func), ELISpot

Specificité: This antibody recognises the p40 subunit of Bovine Interleukin-12, and binds to both the free subunit and the intact heterodimer.

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

niveau d'endotoxine: < 0.01 EU/μg

Clone: CC301

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, None, None

Détails sur IL12B

Antigène: IL12B (Interleukin 12 beta (IL12B))

Autre désignation: Interleukin-12 beta / IL12B (IL12B Produits)

Synonymes: anticorps CLMF, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12, anticorps IL-12 p40, anticorps il12b, anticorps il12p40.b, anticorps zgc:152789, anticorps IL-12.p40, anticorps IL12p40, anticorps IL12B, anticorps CLMF p40, anticorps interleukin 12B, anticorps interleukin 12b, anticorps interleukin 12Ba, anticorps IL12B, anticorps Il12b, anticorps il12ba

Sujet: Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, Interleukin-12B, NK cell stimulatory factor chain 2, NKSF2

ID gène: 281857

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation