IL-2 anticorps

N° du produit ABIN1107821

L’anticorps Souris Monoclonal anti-IL-2 a été validé pour WB, FACS et Func. Il convient pour détecter IL-2 dans des échantillons de Humain.

Aperçu rapide pour IL-2 anticorps (ABIN1107821)

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Functional Studies (Func)

Clone: B-G5

Détail du produit anti-IL-2 anticorps

Specificité: Recognizes both natural and recombinant Human Interleukin-2 (IL-2).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography

Stérilité: 0.22 μm filtered

Immunogène: Natural Human IL-2

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS without Carrier and preservatives. This product is Sterile-filtered through 0.22 μm and treated to remove endotoxins.

Agent conservateur: Without preservative

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IL-2

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Autre désignation: Interleukin-2 / IL2

Sujet: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

ID gène: 3558

NCBI Accession: NP_000577

UniProt: P60568

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation