Lipoprotein Lipase anticorps (C-Term)
Aperçu rapide pour Lipoprotein Lipase anticorps (C-Term) (ABIN1108052)
Antigène
Voir toutes Lipoprotein Lipase (LPL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody detects Lipoprotein lipase (C-term). No cross reactivity with other proteins.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, rat, mouse, bovine
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Purification
- Immunogen affinity purified
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminal of human LPL .Remarks: Sequence is different to the related rat sequence by two amino acids.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Lipoprotein Lipase (LPL)
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Autre désignation
- Lipoprotein Lipase
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Sujet
- Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. Lipoprotein lipase has been difficult to purify, and its protein sequence remained undetermined until it could be deduced from the nucleotide sequence of its cDNA. The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. Analysis of the sequence indicated that human lipoprotein lipase, hepatic lipase, and pancreatic lipase are members of a gene family. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion.Synonyms: EC=3.1.1.34, LIPD, LPL
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ID gène
- 280843
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NCBI Accession
- NP_001068588
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UniProt
- P11151
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Pathways
- Lipid Metabolism
Antigène
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