L’anticorps Lapin Polyclonal anti-Lipoprotein Lipase a été validé pour WB. Il convient pour détecter Lipoprotein Lipase dans des échantillons de Humain et Boeuf (Vache).
This antibody detects Lipoprotein lipase (C-term). No cross reactivity with other proteins.
Réactivité croisée (Details)
Species reactivity (tested):Human, rat, mouse, bovine
Purification
Immunogen affinity purified
Immunogène
A synthetic peptide corresponding to a sequence at the C-terminal of human LPL .Remarks: Sequence is different to the related rat sequence by two amino acids.
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Antigène
Lipoprotein Lipase (LPL)
Autre désignation
Lipoprotein Lipase
Sujet
Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. Lipoprotein lipase has been difficult to purify, and its protein sequence remained undetermined until it could be deduced from the nucleotide sequence of its cDNA. The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. Analysis of the sequence indicated that human lipoprotein lipase, hepatic lipase, and pancreatic lipase are members of a gene family. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion.Synonyms: EC=3.1.1.34, LIPD, LPL