LRP5 anticorps
Aperçu rapide pour LRP5 anticorps (ABIN1108063)
Antigène
Voir toutes LRP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes LRP5
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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Autre désignation
- LRP5
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Sujet
- This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.Synonyms: LRP-5, LRP7, Low-density lipoprotein receptor-related protein 5
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Poids moléculaire
- 179 kDa
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ID gène
- 4041
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Pathways
- Signalisation WNT, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
Antigène
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