Endothelin 1 anticorps (C-Term)

N° du produit ABIN110809

Cet anticorps Rat Monoclonal détecte spécifiquement Endothelin 1 dans RIA et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour Endothelin 1 anticorps (C-Term) (ABIN110809)

Antigène: Endothelin 1 (EDN1)

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Endothelin 1 est non-conjugé

Application: Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3G10

Détail du produit anti-Endothelin 1 anticorps

Épitope: C-Term

Séquence: C-H-L-D-I-I-W

Specificité: Reacts with the C-terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin.

Purification: Protein G affinity chromatography

Immunogène: Synthetic human endothelin-C terminal fragment, conjugated to BSA

Isotype: IgG2b

Information d'application

Indications d'application: RIA / IRMA. Immunohistochemistry on frozen sections: Frozen sections processed with dry acetone are recommended. Paraformaldehyde is notrecommended as it destroys the epitope.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Endothelin 1

Antigène: Endothelin 1 (EDN1)

Autre désignation: Endothelin-1

Sujet: Endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.Synonyms: Big endothelin-1, EDN1, EDN2, ET-2, ET-3, Endothelin-2, Endothelin1, PPET1, PPET2, PPET3, Preproendothelin-1, Preproendothelin-2, Preproendothelin-3

ID gène: 1906

NCBI Accession: NP_001946

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size