M-CSF/CSF1 anticorps

N° du produit ABIN1108092

Cet anticorps anti-M-CSF/CSF1 Monoclonal Rat (Clone ER-MP58) (ABIN1108092) détecte spécifiquement M-CSF/CSF1 dans FACS et IHC (fro). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour M-CSF/CSF1 anticorps (ABIN1108092)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp M-CSF/CSF1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ER-MP58

Détail du produit anti-M-CSF/CSF1 anticorps

Specificité: The monoclonal antibody ER-MP58 recognizes an antigen present on all mouse macrophage colony-stimulating factor (M-CSF) responsive cells in the bone marrow, including the earliest colony-forming myeloid progenitors, as well as by the majority of other myeloid precursors. The antigen is detected on a broad development range of macrophage precursor cells ut to the monocytic level, but also on grnaulocytes. ERxpression is rapidly lost upon maturation beyond the monocytic stage. The antigen disappears in the course of macrophage differentiation. Furthermore the antigen is clearly different from commenly used myeloid markers as Mac-1, F4/80, and Gr-1. The monoclonal antibody ER-MP58 is very useful for the identification of mouse myeloid hemopoietic islands in various organs, and for embryonal studies. Cells committed to the myeloid lineage can be separated from progenitor cells with other differentiation capacities by means of multiparameter cell sorting using monoclonal antibody ER-MP58 in combination with monoclonal antibody ER-MP12 and ER-MP-20.

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Protein G

Immunogène: Balb/c macrophage precursor cell hybrids

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at < -20 °C for at least 6 month.

Date de péremption: 6 months

Détails sur M-CSF/CSF1

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: Macrophage Colony Stimulating Factor (M-CSF)

Sujet: Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1

ID gène: 12977

NCBI Accession: NP_001107001

UniProt: P07141

Pathways: Signalisation RTK