MUC5AC anticorps

N° du produit ABIN1108320

Détail du produit anti-MUC5AC anticorps

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC5AC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: A BALB/c mouse was immunized with Mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classisfication). Splenocytes were fused with mouse myeloma SP2/0 cells.

Clone: 1-13M1

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on cultured cells. Immunochemistry on Frozen Ethanol Fixed Sections. Immunochemistry on Paraffin Sections: a protease pretreatment is recommended. This antibody clone 1-13M1 cross reacts with Mucin of different animal species after period date pretreatment. Immunoblotting: Strongly positive without mercaptoethanol pretreatment of mucin solution. ELISA or IRMA in combination with the clone 9-13M1 or the mixture of anti-M1 Monoclonal antibodies.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MUC5AC

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Autre désignation: Mucin-5AC (MUC5AC Produits)

Synonymes: anticorps MUC5, anticorps TBM, anticorps leB, anticorps 2210005L13Rik, anticorps MGM, anticorps mucin 5AC, oligomeric mucus/gel-forming, anticorps putative gastric mucin, anticorps mucin 5, subtypes A and C, tracheobronchial/gastric, anticorps mucin 2, oligomeric mucus/gel-forming, anticorps MUC5AC, anticorps Smp_144070, anticorps Muc5ac, anticorps MUC2

Sujet: Mucins are high molecular weight glycoproteins that are found especially in the secretions of mucus membranes. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.Synonyms: Gastric mucin, LeB, Lewis B blood group antigen, MUC5, MUC5AC, Major airway glycoprotein, Mucin-5 subtype AC, TBM, Tracheobronchial mucin, tracheobronchial

ID gène: 9606

UniProt: P98088