Ly6g anticorps (Biotin)
Aperçu rapide pour Ly6g anticorps (Biotin) (ABIN1108439)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée (Details)
- Species reactivity (tested):Mouse.
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Purification
- Protein G
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Immunogène
- Purified BALB/c mouse neutrophils
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.02 % Sodium Azide, 0.1 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2 - 8 °C.
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- Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))
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Autre désignation
- Ly6G / GR1 Neutrophil Marker
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Sujet
- The Ly-6G/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear.Synonyms: Gr-1 Granulocyte marker
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ID gène
- 10090
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UniProt
- P35461
Antigène
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