PAX6 anticorps (Internal Region)
Aperçu rapide pour PAX6 anticorps (Internal Region) (ABIN1108593)
Antigène
Voir toutes PAX6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat, Xenopus, Zebrafish.
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- Synthetic peptide derived from internal part of Human PAX6 protein
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore in distilled water.
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Buffer
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PAX6 (Paired Box 6 (PAX6))
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Autre désignation
- PAX6
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Sujet
- PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes.Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6
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ID gène
- 5080
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NCBI Accession
- NP_000271
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Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
Antigène
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