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PLVAP anticorps (FITC)

PLVAP Reactivité: Humain WB, IHC (fro), IF Hôte: Souris Monoclonal 174-2 FITC
N° du produit ABIN1108673
  • Antigène Voir toutes PLVAP Anticorps
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Reactivité
    • 27
    • 7
    • 1
    Humain
    Hôte
    • 21
    • 6
    • 5
    Souris
    Clonalité
    • 22
    • 9
    Monoclonal
    Conjugué
    • 19
    • 4
    • 3
    • 2
    • 2
    • 2
    Cet anticorp PLVAP est conjugé à/à la FITC
    Application
    • 29
    • 22
    • 16
    • 9
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Protein G
    Clone
    174-2
    Isotype
    IgG1
    Top Product
    Discover our top product PLVAP Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 1 % bovine serum albumin
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2 - 8 °C.
  • Antigène
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Autre désignation
    PLVAP (PLVAP Produits)
    Synonymes
    anticorps MECA32, anticorps Pv1, anticorps FELS, anticorps PV-1, anticorps PV1, anticorps gp68, anticorps plasmalemma vesicle associated protein, anticorps Plvap, anticorps PLVAP
    Sujet
    PLVAP is a 60 kDa type II transmembrane glycoprotein which tends to form homodimers. PLVAP is widely expressed in the vasculature of normal tissues. The vascular staining pattern of PLVAP is quite unique among the endothelial cell antigens, since expression of other antigens (like ICAM-1, P-selectin, E-selectin or VCAM-1) is not limited to vascular endothelial cells. PLVAP expression in the vascular endothelial cells of the CNS is lost in association with formation of an intact blood-brain barrier. However, in the endothelium of human brain tumors expression of PLVAP is specifically up-regulated, making it a suitable antiangiogenic target for brain tumor therapy and cerebral edema. Furthermore, PLVAP is expressed in the vasculature of most other human tumors and as such useful as marker for tumor angiogenesis.Synonyms: Endothelial Cell Antigen, Endothelial cell marker, Endothelial cell surface marker, FELS, Fenestrated endothelial-linked structure protein, MECA-32 antigen, PV-1, PV1, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein
    UniProt
    Q9BX97
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