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Polymyxin B anticorps

Reactivité: Bacillus polymyxa WB, EIA Hôte: Souris Monoclonal 45 unconjugated
N° du produit ABIN1108692
  • Antigène Tous les produits Polymyxin B
    Polymyxin B
    Reactivité
    Bacillus polymyxa
    Hôte
    • 1
    Souris
    Clonalité
    • 1
    Monoclonal
    Conjugué
    • 1
    Cet anticorp Polymyxin B est non-conjugé
    Application
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    niveau d'endotoxine
    Low Endotoxin
    Clone
    45
    Isotype
    IgM
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    > 0.2 mg/mL
    Buffer
    0.02 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Polymyxin B
    Abstract
    Polymyxin B Produits
    Sujet
    The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo.
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