EXOSC2 anticorps
Aperçu rapide pour EXOSC2 anticorps (ABIN1108908)
Antigène
Voir toutes EXOSC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Specificity has been tested in ELISA. Additional tests for cross reactivity have not yet been performed.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Immunogène
- Recombinant GST-hRRP4 (NCBI accession number NM_014285 REGION 3-884, expression vector pGEX-4T3), expressed in E.coli.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)
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Buffer
- 10 mM Ammonium Bicarbonate buffer, 2 mg BSA
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Précaution d'utilisation
- Be careful opening the vial since the antibody resides in a vacuum.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- EXOSC2 (Exosome Component 2 (EXOSC2))
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Autre désignation
- RRP4 / EXOSC2
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Sujet
- The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.Synonyms: Exosome complex exonuclease RRP4, Exosome component 2, Ribosomal RNA-processing protein 4
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ID gène
- 23404
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NCBI Accession
- NP_055100
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UniProt
- Q13868
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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